Marco van Ginkel suffered an anterior cruciate ligament injury to his knee during the match at Swindon on 24 September. He made his return to competitive action in an Under-21 League game versus Manchester United on 21 March.

Ashley Cole injured a lateral ligament in his knee in training ahead of the Spurs home game on 8 March. He returned to action during the home game against Stoke on 4 April.

Samuel Eto'o suffered a hamstring injury against Arsenal on 22 March. He returned to play the full game against Paris Saint-Germain on 8 April.

Eden Hazard suffered a calf injury and came off against Paris Saint-Germain on 8 April.