Eden Hazard and N'Golo Kante both return to the side and there is a first Premier League start for Callum Hudson-Odoi
Kante makes his 100th Premier League appearance and he is joined in midfield tonight by Ruben Loftus-Cheek in one of seven changes from the Cardiff game.
Olivier Giroud is up front and in defence, Andreas Christensen and Emerson come in, the latter at left-back in place of injured Marcos Alonso.
Brighton make four changes from their defeat at home to Southampton at the weekend. Bruno, Gaetan Bong, Solly March and Florin Andone come in.
Chelsea (4-3-3): Kepa; Azpilicueta (c), Christensen, David Luiz, Emerson; Kante, Jorginho, Loftus-Cheek; Hudson-Odoi, Giroud, Hazard.
Subs: Caballero, Zappacosta, Rudiger, Barkley, Kovacic, Willian, Higuain.
Brighton (4-3-3): Ryan; Bruno (c), Duffy, Dunk, Bong, Stephens, Propper, Bissouma, Jahanbakhsh, Andone, March.
Subs: Button, Burn, Kayal, Bernardo, Knockaert, Izquierdo, Murray.
Today's referee is Graham Scott.
Chelsea and Brighton meet for only for the eighth occasion in the league (fourth in the top flight) and 12th overall.
We have a 100 per cent record against them in the league and overall we have won nine of the 11 encounters in all competitions.
Brighton have lost each of their past nine games against Chelsea in all competitions, conceding 20 goals and scoring twice in return.
Brighton’s only victory against the Blues was in the third round of the FA Cup in 1932/33. George Barber scored our only goal in a 1-2 defeat.
Maurizio Sarri’s side have lost one Premier League home game so far this season (Leicester in December), and have kept six clean sheets in our past nine at Stamford Bridge, conceding three goals in total during this period.
Cesar Azpilicueta’s equaliser against Cardiff on Sunday was his first of the season, making him the 14th Chelsea player to score in the Premier League in 2018/19. Only Man Utd have had more different scorers this season (15).
Sarri’s side have only committed 280 fouls (nine per game) in the league this season; only Manchester City have conceded fewer (266).
Brighton won their last away Premier League game (2-1 v Crystal Palace), but have not won consecutive league games on the road since November 2017.
Brighton have failed to keep a clean sheet in each of their last 10 away league games.