Maurizio Sarri makes four changes from the side that began Thursday's Europa League game against Slavia Prague.
The defence remains the same, with Andreas Christensen continuing alongside David Luiz in the absence of injured Toni Rudiger, but Jorginho and Ruben Loftus-Cheek both return to the midfield with Mateo Kovacic and Ross Barkley making way.
Up front, Callum Hudson-Odoi and Gonzalo Higuain join Eden Hazard, with Pedro and Olivier Giroud moving to the bench.
Burnley are unchanged from their win over Cardiff last time out.
Chelsea (4-3-3): Arrizabalaga; Azpilicueta (c), Christensen, David Luiz, Emerson; Kante, Jorginho, Loftus-Cheek; Hazard, Higuain, Hudson-Odoi.
Subs Caballero, Zappacosta, Cahill, Kovacic, Barkley, Pedro, Giroud.
Burnley (4-4-2): Heaton (c); Lowton, Tarkowski, Mee, Taylor; Hendrick, Westwood, Cork, McNeil; Barnes, Wood.
Subs Hart, Gibson, Ward, Long, Gudmundsson, Brady, Vydra.
The referee is Kevin Friend
Burnley’s victory on the opening day last season was their first at Stamford Bridge in 11 matches in all competitions. The Blues had won seven and drawn three of the previous 10.
The Clarets previous league win here was on Monday 26 April 1971 when Steve Kindon scored the only goal in the old First Division.
Burnley are looking to win back to back away games against Chelsea for the first time since December 1961.
Thirty-three per cent of Chelsea’s goals in the Premier League this season have been scored in the final 15 minutes.
Eden Hazard has scored in 50 home games without ending on the losing side, winning 42 and drawing eight.
Hazard has been fouled 97 times (21 resulting in a yellow card) in the league this season, more than any other Chelsea player.
At Liverpool last week, aged 18 years 158 days, Callum Hudson-Odoi became the youngest Chelsea player to start three consecutive Premier League games.
No side has conceded fewer home league goals than the Blues (10, equal with Liverpool).
Burnley have only failed to score in one of their last 11 games in the Premier League, with that coming in a 0-2 defeat against Newcastle in February.
Sean Dyche’s side have had fewer shots on goal this season than any other Premier League side (248).