Frank Lampard names an unchanged side.
In selecting the side that beat Aston Villa midweek, Lampard keeps Andreas Christensen as Kurt Zouma's partner in central defence with the midfield three maintained as N'Golo Kante, Mateo Kovacic and Mason Mount.
Willian, in the front three, starts for the 150th time in the Premier League. Ross Barkley returns to the bench for this game against his former side.
Lampard is expecting a tough test against a side who parted ways with manager Marco Silva this week. 'It means potentially a more dangerous game for us,' he said on arrival at Goodison Park.
'We all know there can be a bounce effect when you make a change, particularly when you bring a club legend like Duncan Ferguson into the equation, with the way he played the game.
'I expect them to have a real go so it's up to us to counter that with how we play and how aggressive we can be because we want to come here and win.
'We were really good against Villa and the only thing we didn't do was score more goals but I was really pleased. It's a tight turnaround but I expect more of the same from us.'
Morgan Schneiderlin and Theo Walcott come into the first Everton side selected by Ferguson.
Chelsea Kepa; James, Christensen, Zouma, Azpilicueta (c); Kante, Kovacic, Mount; Willian, Abraham, Pulisic.
Subs Caballero, Tomori, Emerson, Jorginho, Barkley, Hudson-Odoi, Batshuayi.
Everton Pickford; Sidibe, Keane, Holgate, Digne; Walcott, Schneiderlin, Sigurdsson (c), Iwobi; Richarlison, Calvert-Lewin.
Subs Steckelenberg, Baines, Davies, Niasse, Tosun, Bernard, Kean.
The referee is Craig Pawson.
Everton are looking to secure consecutive league wins against Chelsea for the first time since November 1994.
Chelsea have not scored in our last three Premier League games against Everton. We have never gone four consecutive games without a goal against an opponent in the competition, last doing so in the top flight against Bolton (1958-1960).
Everton have won six of their last 10 home league games against Chelsea.
This weekend’s game will be our 89th competitive visit to Goodison Park, more times than we have played at any other away ground.
Chelsea have won more games in all competitions against Everton than against any other club - 72
We have also scored more goals against the Toffees than against any other side - 285
Chelsea have scored 19 goals in our seven away league games this season – we have never scored more after seven games on the road in a single league campaign (level with 1966/67 and 2008/09). The Blues are averaging 6.7 shots on target per away game this season, our highest in a Premier League campaign since at least 2003/04.
63 per cent of our league goals this term have been scored away.
Tammy Abraham has been involved in 14 goals in his 14 Premier League appearances this season (11 goals, three assists).
Frank Lampard’s side have the third-best away record in the Premier League this season with 15 points from seven games, one point behind Man City and four behind Liverpool.