Mason Mount returns to the starting line-up in the only change from the team that began against Lille on Tuesday.
Mateo Kovacic makes way with Jorginho and N'Golo Kante the other midfielders selected.
Fit-again Toni Rudiger plays again alongside Kurt Zouma in central defence.
Former Chelsea striker Dominic Solanke is on the Bournemouth bench. Callum Wilson and Harry Wilson are missing for the Cherries but Josh King returns.
Chelsea Kepa, Azpilicueta (c), Rudiger, Zouma, Emerson; Kante, Jorginho, Mount; Willian, Abraham, Pulisic.
Subs Caballero, Christensen, James, Kovacic, Pedro, Hudson-Odoi, Batshuayi.
Bournemouth Ramsdale; Stacey, Francis (c), Mepham, Rico; Billing, Lerma, L Cook, Gosling; Fraser, King.
Subs Boruc, Surman, Simpson, Kilkenny, Dobre, Stanislas, Solanke.
The referee is Graham Scott
Bournemouth have won two of their past three league games against Chelsea with the Blues winning the other.
None of the 15 meetings between Chelsea and Bournemouth in all competitions have ended in a draw, with the Blues winning 11 of those.
Since Bournemouth were promoted to the Premier League in 2015, only Liverpool (three) have beaten Chelsea at Stamford Bridge in the competition more often than the Cherries (two).
Frank Lampard’s side have won four of our last five Premier League games at Stamford Bridge.
We are hoping to halt a run of three defeats in our last four Premier League games.
Only Manchester City (337) have had more shots than Chelsea in the Premier League this season (274). The Blues’ average of 17.1 shots per game is our highest in a single campaign since 2013/14 (18.2).
Chelsea haven’t drawn any of our last 12 Premier League games since the 2-2 draw with Sheffield United in August – the second current longest such run behind Leicester (14).