Gonzalo Higuain comes back into the side to lead the line for tonight's FA Cup game and Eden Hazard also starts.
Toni Rudiger returns to partner David Luiz in the centre of defence while Marcos Alonso starts at left-back.
In midfield, N'Golo Kante replaces Ross Barkley, a scorer in Malmo on Thursday, and it will be Hazard and Pedro supporting Higuain.
Three former Chelsea players - Nemanja Matic, Juan Mata and Romelu Lukaku - start for the visitors.
Kepa; Azpilicueta (c), Rudiger, David Luiz, Alonso; Kante, Jorginho, Kovacic; Pedro, Higuain, Hazard.
Subs: Caballero, Christensen, Zappacosta, Barkley, Hudson-Odoi, Willian, Giroud.
Romero, Young (c), Lindelof, Smalling, Shaw, Herrera, Matic, Pogba, Mata, Lukaku, Rashford.
Subs: De Gea, Bailly, Dalot, Fred, McTominay, Perreira, Sanchez.
Chelsea are in the FA Cup fifth round for the 19th time in 21 years – two more than any other team has ever achieved over a 21-year period.
We are now seeking to reach the quarter-final for the 13th time in 18 seasons and 37th overall.
The Blues have won our last 10 home FA Cup games, including the one on penalties against Norwich last season. League One side Bradford City were the last team to defeat us at home in the competition in 2015 in the fourth round.
Chelsea have scored in all 47 FA Cup games we have played at home since January 2000.
The last team to keep a clean sheet at Stamford Bridge in the FA Cup was Manchester United in the quarter-final in 1999.