There are six changes to the side that lined up to start the FA Cup final a week ago, including a welcome return to action for N’Golo Kante.
Many of the alterations have been forced upon Frank Lampard, with Jorginho and Marcos Alonso suspended alongside injuries to a host of others.
It means the Blues revert to a back four, with Andreas Christensen returning to partner Kurt Zouma in central defence. Reece James and Emerson start at full-back in front of Willy Caballero.
Tammy Abraham leads the line up front supported by Mason Mount and Callum Hudson-Odoi, the latter making his first start since the opening day of February. Ross Barkley is in midfield alongside Mateo Kovacic and Kante, who is tonight’s captain.
There are milestones for two Chelsea Academy graduates, with Christensen making his 100th Blues appearance and Abraham his 50th in all competitions.
Chelsea (4-3-3) Caballero; James, Zouma, Christensen, Emerson; Kante (c), Kovacic, Barkley; Hudson-Odoi, Abraham, Mount
Subs Kepa, Cumming, Rudiger, Tomori, Simeu, Maatsen, Bate, Lawrence, Giroud, Batshuayi, Broja
Bayern (4-2-3-1) Neuer; Kimmich, Boateng, Alaba, Davies; Goretzka, Thiago Alcantara; Gnabry, Muller, Perisic; Lewandowski
Subs Ulreich, Hoffmann, Odriozola, Sule, Javi Martinez, Coutinho, Cuisance, Hernandez, Tolisso, Tillman, Musiala, Arrey-Mbi
Chelsea are currently unbeaten in a club-record 10 away European matches, since losing 0-3 to Barcelona in the Champions League round of 16 in 2018 (seven wins, three draws).
We have not won any of our last seven away Champions League matches in the knockout stages (four draws, three defeats), since a 1-0 win at Benfica in March 2012 in the quarter-final.
Chelsea have scored three goals in an away Champions League knockout match once previously, winning 3-1 at Liverpool in April 2009.
Our record in the round of 16 is eight wins and five defeats. We have lost our last three contests at this stage, most recently going down 1-4 on aggregate to Barcelona (1-1 h, 0-3 a) in 2017/18.
Last season's Europa League draw at Eintracht Frankfurt extended Chelsea's unbeaten run in Germany to four matches (two wins, two draws), since a 1-2 defeat at Bayer Leverkusen in the 2011/12 Champions League group stage.
Olivier Giroud has scored in eight of his past 10 starts for the Blues.
Chelsea's 2019/20 Champions League scorers:
Abraham 2, Azpilicueta 2, Jorginho 2 (2 pens), Batshuayi 1, James 1, Kovacic 1, Pulisic 1, Willian 1