Thomas Tuchel has made five changes for his final selection of the 2021/22 season.
Kai Havertz returns in attack, as does Mason Mount with Hakim Ziyech retaining his place.
The captain Cesar Azpilicueta is also back in a defence that contains Toni Rudiger for the final time in a Chelsea shirt. Saul is chosen to play alongside N’Golo Kante in midfield and there is a first league game of the season for Kenedy, who is expected to play at left wing-back.
There is a place for Ben Chilwell among the subs, the first time he has been in the squad since his knee injury against Juventus six months ago.
In his final game in charge of Watford, Roy Hodgson has made six changes from their heavy defeat by Leicester.
Watford: Bachmann, Femenia, Kabasele, Samir, Kamara, Sissoko (c), Kayembe, Cleverley, Joao Pedro, King, Sema.
Subs: Elliot, Ngakia, Troost-Ekong, Masina, Cathcart, Gosling, Hernandez, Sierralta, Baah.
The referee is Mike Dean.