Cesar Azpilicueta makes his 300th Premier League appearance for Chelsea on his 32nd birthday as the Blues make one change from last weekend's win at Arsenal.
That one alteration sees N'Golo Kante replace Mateo Kovacic in central midfield alongside Jorginho.
In attack, Romelu Lukaku leads the line once again supported by Kai Havertz and Mason Mount.
Edouard Mendy continues in goal behind a back three of Azpilicueta, Andreas Christensen and Toni Rudiger, while Reece James and Marcos Alonso are preferred at wing-back.
Jurgen Klopp makes three changes for Liverpool as Andy Robertson, Fabinho and Roberto Firmino come in.
Chelsea (3-4-3): Mendy; Azpilicueta (c), Christensen, Rudiger; James, Jorginho, Kante, Alonso; Havertz, Lukaku, Mount
Subs: Kepa, Chilwell, Chalobah, Thiago Silva, Kovacic, Loftus-Cheek, Hudson-Odoi, Ziyech, Werner
Liverpool (4-3-3): Alisson; Alexander-Arnold, Matip, Van Dijk, Robertson; Henderson (c), Fabinho, Elliott; Mane, Firmino, Salah
Subs: Kelleher, Gomez, Konate, Tsimikas, Keita, Thiago, Minamino, Oxlade-Chamberlain, Jota
The referee is Anthony Taylor.