There is one change to the side which began the win against Newcastle at the weekend.
That is the return of Mateo Kovacic who comes in for the injured Ross Barkley.
Our two goalscorers in the previous Champions League outing away in Lille, Tammy Abraham and Willian, are joined in attack by Callum Hudson-Odoi who starts in this competition for the first time.
Cesar Azpilicueta will play his 350th Chelsea game.
Fit-again Emerson Palmieri is on the bench.
Ajax name the same side as their 3-0 away win in Valencia on Matchday Two.
Chelsea Kepa; Azpilicueta (c), Zouma, Tomori, Alonso; Kovacic, Jorginho, Mount; Willian, Abraham, Hudson-Odoi.
Substitutes Caballero, James, Emerson, Gilmour, Pulisic, Batshuayi, Giroud.
Ajax Onana; Dest, Veltman, Blind, Tagliafico; Alvarez, Martinez; Ziyech, Van de Beek, Promes; Tadic (c).
Substitutes: Varela, Schuurs, Mazraoui, Neres, De Jong, Marin, Huntelaar.
The referee is Ovidiu Hategan from Romania.
Both Chelsea and Ajax are seeking a sixth successive win in all competitions.Chelsea are hoping for a sixth successive win in all competitions for the first time since September 2018.Chelsea and Ajax have never met before in European competition although we have played each other six times in non-competitive pre-season matches.
Chelsea are unbeaten in four previous European games with Dutch sides (two wins, two draws), winning twice against Feyenoord in the 1999/00 Champions League second group stage and drawing two knockout games goalless against DWS Amsterdam in the 1968/69 Fairs Cup, going out after losing a coin toss.Although we have never played Ajax in European competition before, we played at their stadium against Benfica in the 2013 Europa League final.Chelsea are looking to win consecutive away Champions League matches for the first time since October 2013, when we beat Steaua Bucharest and Schalke.Chelsea have won four of our past five away group games in the Champions League, scoring 12 and conceding five.